About 1 result found for searched term "GSK215 " (0.222 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29789 | GSK215 | FAK |
| GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader with a pDC50 of 8.4. GSK215 is designed by a binder for the VHL E3 ligase and the FAK inhibitor VS-4718. GSK215 induces rapid and prolonged FAK degradation, giving a long-lasting effect on FAK levels and a marked pharmacokinetic/pharmacodynamics (PK/PD) disconnect. | ||
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